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CAS 1309876-75-2
3-(3-[[(Carboxymethyl)[2-[(carboxymethyl)([2-hydroxy-5-[3-oxo-3-(2,3,5,6-tetrafluorophenoxy)propyl]phenyl]methyl)amino]ethyl]amino]methyl]-4-hydroxyphenyl)propanoic acid
Codes: (V)828549-1-a,(V)828549-1-b
Application context (from source-drug indications)
Prostate cancerTLX-591 companion diagnostic (Telix Pharmaceuticals)Diagnostic agentTLX-591 companion diagnostic (Telix Pharmaceuticals)Castration-resistant prostate cancerTLX-591 companion diagnostic (Telix Pharmaceuticals)Hepatocellular carcinomaTLX-591 companion diagnostic (Telix Pharmaceuticals)Castration-sensitive prostate cancerTLX-591 companion diagnostic (Telix Pharmaceuticals)Bladder cancerTLX-591 companion diagnostic (Telix Pharmaceuticals)
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| TLX-591 companion diagnostic (Telix Pharmaceuticals) | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
Resin bound (2S)-6-amino-2-([[(2S)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl]carbamoyl]amino)hexanoic acid→6-([[(9H-Fluoren-9-yl)methoxy]carbonyl]amino)hexanoic acid→Resin bound (2S)-6-[(6-Aminohexanoyl)amino]-2-([[(2S)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl]carbamoyl]amino)hexanoic acid→(2S)-6-[(6-Aminohexanoyl)amino]-2-([[(2S)-1,5-di-tert-butoxy-1,5-dioxopentan-2-yl]carbamoyl]amino)hexanoic acid→3-(3-[[(Carboxymethyl)[2-[(carboxymethyl)([2-hydroxy-5-[3-oxo-3-(2,3,5,6-tetrafluorophenoxy)propyl]phenyl]methyl)amino]ethyl]amino]methyl]-4-hydroxyphenyl)propanoic acid→N-[[(1S)-1-Carboxy-5-([6-[3-(3-[[[2-[[[5-(2-carboxyethyl)-2-hydroxyphenyl]methyl](carboxymethyl)amino]ethyl](carboxymethyl)amino]methyl]-4-hydroxyphenyl)propanamido]hexanoyl]amino)pentyl]carbamoyl]-L-glutamic acid
3-(3-[[(Carboxymethyl)[2-[(carboxymethyl)([2-hydroxy-5-[3-oxo-3-(2,3,5,6-tetrafluorophenoxy)propyl]phenyl]methyl)amino]ethyl]amino]methyl]-4-hydroxyphenyl)propanoic acid→3-(4-Hydroxyphenyl)propionic acid→2,2'-(Ethane-1,2-diyldiazanediyl)diacetic acid→3,3'-(Ethane-1,2-diylbis[[(carboxymethyl)azanediyl]methylene(4-hydroxy-3,1-phenylene)])dipropanoic acid→2,2'-[Ethane-1,2-diylbis([[5-(2-carboxyethyl)-2-oxidophenyl]methyl]azanediyl)]diacetate iron(3+)→[[2-[[[5-(2-Carboxyethyl)-2-oxidophenyl]methyl](carboxylatomethyl)amino]ethyl]([2-oxido-5-[3-oxo-3-(2,3,5,6-tetrafluorophenoxy)propyl]phenyl]methyl)amino]acetate iron(3+)
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