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福他替尼二钠六水合物

Tier C — Watch / trade

Fostamatinib disodium hexahydrate

Rigel Pharmaceuticals Inc
Originator
2018
First approval
-
Expiry (public)
$0.02B ▲
Peak sales
化学药
Type

TargetsSyk

Brandタバリス、Tavalisse、Tavlesse

Indications (approved)特发性血小板减少性紫癜、血小板减少

Regional status

US
批准上市
2018-04-17
EU
批准上市
2020-01-09
China
申请上市
2022-06-15
Japan
批准上市
2022-12-23

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 4 · Total yield 8.18
Synthetic routes & intermediates Route 1
CodeCAS No.Intermediate
FOST-001575484-83-2Available6-[(2-chloro-5-fluoropyrimidin-4-yl)amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one
FOST-00224313-88-0Available3,4,5-trimethoxyaniline
FOST-003841290-80-0Available6-((5-fluoro-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)amino)-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
FOST-004229625-50-7Availabledi-tert-butyl (chloromethyl) phosphate
FOST-005901119-38-8Availabledi-tert-butyl ((6-((5-fluoro-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)amino)-2,2-dimethyl-3-oxo-2H-pyrido[3,2-b][1,4]oxazin-4(3H)-yl)methyl) phosphate
FOST-006901119-35-5Available(6-((5-fluoro-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)amino)-2,2-dimethyl-3-oxo-2H-pyrido[3,2-b][1,4]oxazin-4(3H)-yl)methyl dihydrogen phosphate

Frequently asked questions

What are the approved indications of Fostamatinib disodium hexahydrate?

Approved indications include: 特发性血小板减少性紫癜, 血小板减少.

When does the Fostamatinib disodium hexahydrate patent expire?

No public expiry year is available for Fostamatinib disodium hexahydrate yet; this page updates once verified.

How many synthesis routes are recorded for Fostamatinib disodium hexahydrate?

1 synthesis routes are recorded; the shortest is 4 steps with 8.18 total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Fostamatinib disodium hexahydrate intermediates?

6 intermediate CAS of Fostamatinib disodium hexahydrate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Fostamatinib disodium hexahydrate intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-24