达塞布韦钠
Tier C — Watch / tradeDasabuvir Sodium Hydrate
Targets：NS5B
Brand：Exviera
Indications (approved)：慢性丙型肝炎
Regional status
Synthetic routes & intermediates4 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| DASA-016 | 73183-34-3Available | 4,4,4',4',5,5,5',5'-octamethyl-2,2'-bi(1,3,2-dioxaborolane) |
| DASA-001 | 88-18-6 | 2-(tert-butyl)phenol |
| DASA-002 | 6683-81-4 | 2-(tert-butyl)-4-nitrophenol |
| DASA-003 | 20294-59-1 | 2-bromo-6-(tert-butyl)-4-nitrophenol |
| DASA-004 | 1132940-55-6 | 1-bromo-3-(tert-butyl)-2-methoxy-5-nitrobenzene |
| DASA-005 | 1132940-59-0 | 3-bromo-5-(tert-butyl)-4-methoxyaniline |
| DASA-006 | 1132940-57-8 | tert-butyl (3-bromo-5-(tert-butyl)-4-methoxyphenyl)carbamate |
| DASA-007 | 1132940-88-5 | N-(6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-2-yl)methanesulfonamide |
| DASA-008 | 1132940-90-9 | tert-butyl (3-(tert-butyl)-4-methoxy-5-(6-(methylsulfonamido)naphthalen-2-yl)phenyl)carbamate |
| DASA-009 | - | N-(6-(5-amino-3-(tert-butyl)-2-methoxyphenyl)naphthalen-2-yl)methanesulfonamide |
| DASA-010 | 201487-06-1 | (E)-3-methoxyacryloyl isocyanate |
| DASA-011 | - | (E)-N-((3-(tert-butyl)-4-methoxy-5-(6-(methylsulfonamido)naphthalen-2-yl)phenyl)carbamoyl)-3-methoxyacrylamide |
| DASA-012 | 33626-98-1 | methyl 6-bromo-2-naphthoate |
| DASA-013 | 5773-80-8 | 6-bromo-2-naphthoic acid |
| DASA-014 | 7499-66-3 | 6-bromonaphthalen-2-amine |
| DASA-015 | 1132940-86-3 | N-(6-bromonaphthalen-2-yl)methanesulfonamide |
| Code | CAS No. | Intermediate |
|---|---|---|
| DASA-001 | 88-18-6 | 2-(tert-butyl)phenol |
| DASA-007 | 1132940-88-5 | N-(6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-2-yl)methanesulfonamide |
| DASA-017 | 60803-26-1 | 2-(tert-butyl)-4,6-diiodophenol |
| DASA-018 | 1132940-51-2 | 1-(tert-butyl)-3,5-diiodo-2-methoxybenzene |
| DASA-019 | 66-22-8 | pyrimidine-2,4(1H,3H)-dione |
| DASA-020 | 1132940-53-4 | 1-(3-(tert-butyl)-5-iodo-4-methoxyphenyl)pyrimidine-2,4(1H,3H)-dione |
| Code | CAS No. | Intermediate |
|---|---|---|
| DASA-001 | 88-18-6 | 2-(tert-butyl)phenol |
| DASA-002 | 6683-81-4 | 2-(tert-butyl)-4-nitrophenol |
| DASA-007 | 1132940-88-5 | N-(6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-2-yl)methanesulfonamide |
| DASA-010 | 201487-06-1 | (E)-3-methoxyacryloyl isocyanate |
| DASA-020 | 1132940-53-4 | 1-(3-(tert-butyl)-5-iodo-4-methoxyphenyl)pyrimidine-2,4(1H,3H)-dione |
| DASA-021 | 32750-26-8 | 2-(tert-butyl)-6-iodo-4-nitrophenol |
| DASA-022 | 1132940-43-2 | 1-(tert-butyl)-3-iodo-2-methoxy-5-nitrobenzene |
| DASA-023 | 1132940-45-4 | 3-(tert-butyl)-5-iodo-4-methoxyaniline |
| DASA-024 | 1132940-47-6 | (E)-N-((3-(tert-butyl)-5-iodo-4-methoxyphenyl)carbamoyl)-3-methoxyacrylamide |
| Code | CAS No. | Intermediate |
|---|---|---|
| DASA-001 | 88-18-6 | 2-(tert-butyl)phenol |
| DASA-017 | 60803-26-1 | 2-(tert-butyl)-4,6-diiodophenol |
| DASA-018 | 1132940-51-2 | 1-(tert-butyl)-3,5-diiodo-2-methoxybenzene |
| DASA-019 | 66-22-8 | pyrimidine-2,4(1H,3H)-dione |
| DASA-020 | 1132940-53-4 | 1-(3-(tert-butyl)-5-iodo-4-methoxyphenyl)pyrimidine-2,4(1H,3H)-dione |
| DASA-025 | 173194-95-1 | (6-hydroxynaphthalen-2-yl)boronic acid |
| DASA-026 | 1355646-93-3 | 1-(3-(tert-butyl)-5-(6-hydroxynaphthalen-2-yl)-4-methoxyphenyl)pyrimidine-2,4(1H,3H)-dione |
| DASA-027 | 1355646-97-7 | 6-[3-Tert-Butyl-5-(2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)-2-Methoxyphenyl]-2-Naphthyl 1,1,2,2,3,3,4,4,4-Nonafluorobutane-1-Sulfonate |
| DASA-028 | 3144-09-0 | methanesulfonamide |
Frequently asked questions
What are the approved indications of Dasabuvir Sodium Hydrate?
Approved indications include: 慢性丙型肝炎.
When does the Dasabuvir Sodium Hydrate patent expire?
No public expiry year is available for Dasabuvir Sodium Hydrate yet; this page updates once verified.
How many synthesis routes are recorded for Dasabuvir Sodium Hydrate?
4 synthesis routes are recorded; the shortest is 4 steps with 20.74 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Dasabuvir Sodium Hydrate intermediates?
1 intermediate CAS of Dasabuvir Sodium Hydrate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Dasabuvir Sodium Hydrate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24