磷酸阿米吡啶
Tier C — Watch / tradeAmifampridine Phosphate
Targets：Potassium channel、VGKCs
Brand：FIRDAPSE、Zenas、Firdapse
Indications (approved)：郎伯综合征
Regional status
Synthetic routes & intermediates2 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| AMIF-001 | 626-64-2 | pyridin-4-ol |
| AMIF-002 | 5435-54-1 | 3-nitropyridin-4-ol |
| AMIF-003 | 94602-04-7 | 4-ethoxy-3-nitropyridine hydrochloride |
| AMIF-004 | 1681-37-4 | 3-nitropyridin-4-amine |
| Code | CAS No. | Intermediate |
|---|---|---|
| AMIF-004 | 1681-37-4 | 3-nitropyridin-4-amine |
| AMIF-005 | 504-24-5 | pyridin-4-amine |
| AMIF-006 | 5221-42-1 | N-(3-nitropyridin-4-yl)acetamide |
| AMIF-007 | 79371-42-9 | N-(pyridin-4-yl)acetamide |
Frequently asked questions
What are the approved indications of Amifampridine Phosphate?
Approved indications include: 郎伯综合征.
When does the Amifampridine Phosphate patent expire?
No public expiry year is available for Amifampridine Phosphate yet; this page updates once verified.
How many synthesis routes are recorded for Amifampridine Phosphate?
2 synthesis routes are recorded; the shortest is 4 steps with 535 mg total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Amifampridine Phosphate intermediates?
All intermediates in Amifampridine Phosphate routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Amifampridine Phosphate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24