酒石酸伐尼克兰
Tier B — Position earlyVarenicline Tartrate
Targets：Nicotinic acetylcholine receptor alpha-4/beta-2
Brand：Chantix/Champix、Chantix、畅沛、Champix
Indications (approved)：尼古丁依赖、吸烟戒断、戒烟
Regional status
Synthetic routes & intermediates3 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| VARE-008 | 230615-69-7Available | 1-(7,8-diamino-1,2,4,5-tetrahydro-3H-1,5-methanobenzo[d]azepin-3-yl)-2,2,2-trifluoroethan-1-one |
| VARE-009 | 230615-70-0Available | 2,2,2-trifluoro-1-(6,7,9,10-tetrahydro-8H-6,10-methanoazepino[4,5-g]quinoxalin-8-yl)ethan-1-one |
| VARE-001 | 1072-85-1Available | 1-bromo-2-fluorobenzene |
| VARE-002 | 4453-90-1Available | 1,4-dihydro-1,4-methanonaphthalene |
| VARE-003 | 230615-47-1Available | 1,2,3,4-tetrahydro-1,4-methanonaphthalene-2,3-diol |
| VARE-004 | 230615-48-2Available | 3-benzyl-2,3,4,5-tetrahydro-1H-1,5-methanobenzo[d]azepine |
| VARE-005 | 69718-72-5Available | 2,3,4,5-tetrahydro-1H-1,5-methanobenzo[d]azepine |
| VARE-006 | 230615-51-7Available | 2,2,2-trifluoro-1-(1,2,4,5-tetrahydro-3H-1,5-methanobenzo[d]azepin-3-yl)ethan-1-one |
| VARE-007 | 230615-59-5Available | 1-(7,8-dinitro-1,2,4,5-tetrahydro-3H-1,5-methanobenzo[d]azepin-3-yl)-2,2,2-trifluoroethan-1-one |
| Code | CAS No. | Intermediate |
|---|---|---|
| VARE-006 | 230615-51-7Available | 2,2,2-trifluoro-1-(1,2,4,5-tetrahydro-3H-1,5-methanobenzo[d]azepin-3-yl)ethan-1-one |
| VARE-010 | 19472-74-3Available | 2-(2-bromophenyl)acetonitrile |
| VARE-011 | 34846-90-7Available | methyl (E)-3-methoxyacrylate |
| VARE-012 | 474024-29-8Available | methyl (Z)-4-(2-bromophenyl)-4-cyanobut-3-enoate |
| VARE-013 | 474024-30-1Available | sodium (Z)-(3-cyano-1H-inden-1-ylidene)(methoxy)methanolate |
| VARE-014 | 357426-12-1Available | methyl 3-(aminomethyl)-2,3-dihydro-1H-indene-1-carboxylate |
| VARE-015 | 357426-13-2Available | 1,3,4,5-tetrahydro-2H-1,5-methanobenzo[d]azepin-2-one |
| VARE-016 | 357425-93-5Available | 2,3,4,5-tetrahydro-1H-1,5-methanobenzo[d]azepin-3-ium 4-methylbenzenesulfonate |
| Code | CAS No. | Intermediate |
|---|---|---|
| VARE-005 | 69718-72-5Available | 2,3,4,5-tetrahydro-1H-1,5-methanobenzo[d]azepine |
| VARE-017 | 100-46-9Available | phenylmethanamine |
| VARE-018 | 615-13-4Available | 1H-inden-2(3H)-one |
| VARE-019 | 1416960-04-7Available | 3-benzyl-2,3,4,5-tetrahydro-1H-1,5-methanobenzo[d]azepin-10-one |
Frequently asked questions
What are the approved indications of Varenicline Tartrate?
Approved indications include: 尼古丁依赖, 吸烟戒断, 戒烟.
When does the Varenicline Tartrate patent expire?
No public expiry year is available for Varenicline Tartrate yet; this page updates once verified.
How many synthesis routes are recorded for Varenicline Tartrate?
3 synthesis routes are recorded; the shortest is 2 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Varenicline Tartrate intermediates?
19 intermediate CAS of Varenicline Tartrate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Varenicline Tartrate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24