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Landiolol Hydrochloride

Tier C — Watch / trade

Landiolol Hydrochloride

-
Originator
2002
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:ADRB1

Brand:Onoact, Rapiblyk, Corebeta, Rapibloc

Indications (approved):Supraventricular tachycardia, 室性心律失常, Arrhythmia, 窦性心动过速, Atrial fibrillation, Atrial flutter

Regional status

US
Approved
2024-11-22
EU
Phase II
2021-03-03
China
Approved
2020-12-11
Japan
Approved
2002-07-05

Synthetic routes & intermediates2 routes

Originator routes × 1Optimised (non-patent) × 1Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 4 · Total yield /
LAND-00160827-45-4LAND-002116-11-0LAND-00360456-22-6LAND-004501-97-3LAND-005144256-11-1LAND-00696479-96-8LAND-007144256-12-2LAND-00869630-16-6API · Landiolol Hydrochloride
CodeCAS No.Intermediate
LAND-00160827-45-4(S)-3-chloropropane-1,2-diol
LAND-002116-11-02-methoxyprop-1-ene
LAND-00360456-22-6(S)-4-(chloromethyl)-2,2-dimethyl-1,3-dioxolane
LAND-004501-97-33-(4-hydroxyphenyl)propanoic acid
LAND-005144256-11-1(S)-(2,2-dimethyl-1,3-dioxolan-4-yl)methyl 3-(4-hydroxyphenyl)propanoate
LAND-00696479-96-8(S)-2-(bromomethyl)oxirane
LAND-007144256-12-2((S)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl 3-(4-(((S)-oxiran-2-yl)methoxy)phenyl)propanoate
LAND-00869630-16-6N-(2-aminoethyl)morpholine-4-carboxamide
OptimisedRoute 2Steps 3 · Total yield 0.48 g
LAND-005144256-11-1LAND-00967843-74-7LAND-010—LAND-0111398109-46-0LAND-012—API · Landiolol Hydrochloride
CodeCAS No.Intermediate
LAND-005144256-11-1(S)-(2,2-dimethyl-1,3-dioxolan-4-yl)methyl 3-(4-hydroxyphenyl)propanoate
LAND-00967843-74-7Available(S)-2-(chloromethyl)oxirane
LAND-010--
LAND-0111398109-46-0((S)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl 3-(4-((R)-3-chloro-2-hydroxypropoxy)phenyl)propanoate
LAND-012-N-(2-aminoethyl)morpholine-4-carboxamide oxalate

Frequently asked questions

What are the approved indications of Landiolol Hydrochloride?

Approved indications include: Supraventricular tachycardia, 室性心律失常, Arrhythmia, 窦性心动过速, Atrial fibrillation, Atrial flutter.

When does the Landiolol Hydrochloride patent expire?

No public expiry year is available for Landiolol Hydrochloride yet; this page updates once verified.

How many synthesis routes are recorded for Landiolol Hydrochloride?

2 synthesis routes are recorded; the shortest is 3 steps with 0.48 g total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Landiolol Hydrochloride intermediates?

1 intermediate CAS of Landiolol Hydrochloride are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Landiolol Hydrochloride intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-27