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CAS 1398109-46-0

((S)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl 3-(4-((R)-3-chloro-2-hydroxypropoxy)phenyl)propanoate

Codes: LAND-011

Application context (from source-drug indications)

Supraventricular tachycardiaLandiolol Hydrochloride室性心律失常Landiolol HydrochlorideArrhythmiaLandiolol Hydrochloride窦性心动过速Landiolol HydrochlorideAtrial fibrillationLandiolol HydrochlorideAtrial flutterLandiolol Hydrochloride

Source drugs (routes using this intermediate)

DrugTierExpiry
Landiolol HydrochlorideTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Landiolol HydrochlorideOptimised routesteps: 3total yield: 0.48 g
(S)-(2,2-dimethyl-1,3-dioxolan-4-yl)methyl 3-(4-hydroxyphenyl)propanoate→(S)-2-(chloromethyl)oxirane→LAND-010→((S)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl 3-(4-((R)-3-chloro-2-hydroxypropoxy)phenyl)propanoate→N-(2-aminoethyl)morpholine-4-carboxamide oxalate

Intermediates available on this site

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