盐酸安罗替尼
Tier C — Watch / tradeAnlotinib Dihydrochloride
Targets：VEGFR1、KIT、VEGFR3、PDGFR-β、FGFR1、FGFR3、FGFR2、VEGFR2
Brand：福可维
Indications (approved)：肺泡软组织肉瘤、肝细胞癌、子宫内膜癌、甲状腺瘤、甲状腺髓样癌、小细胞肺癌、肉瘤、非小细胞肺癌
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| ANLO-001 | 6914-71-2 | dimethyl cyclopropane-1,1-dicarboxylate |
| ANLO-002 | 113020-21-6 | 1-(methoxycarbonyl)cyclopropane-1-carboxylic acid |
| ANLO-003 | 88157-42-0 | methyl 1-(hydroxymethyl)cyclopropane-1-carboxylate |
| ANLO-004 | 498-02-2 | 1-(4-hydroxy-3-methoxyphenyl)ethan-1-one |
| ANLO-005 | 1058137-71-5 | methyl 1-((4-acetyl-2-methoxyphenoxy)methyl)cyclopropane-1-carboxylate |
| ANLO-006 | 1058157-33-7 | methyl 1-((4-acetyl-2-methoxy-5-nitrophenoxy)methyl)cyclopropane-1-carboxylate |
| ANLO-007 | 1058137-72-6 | methyl 1-((4-acetyl-5-amino-2-methoxyphenoxy)methyl)cyclopropane-1-carboxylate |
| ANLO-008 | 1058137-73-7 | methyl 1-(((4-hydroxy-6-methoxyquinolin-7-yl)oxy)methyl)cyclopropane-1-carboxylate |
| ANLO-009 | 1058137-74-8 | methyl 1-(((4-chloro-6-methoxyquinolin-7-yl)oxy)methyl)cyclopropane-1-carboxylate |
| ANLO-010 | 288385-88-6 | 4-fluoro-2-methyl-1H-indol-5-ol |
| ANLO-011 | 1058156-57-2 | methyl 1-(((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinolin-7-yl)oxy)methyl)cyclopropane-1-carboxylate |
| ANLO-012 | 1058156-60-7 | 1-(((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinolin-7-yl)oxy)methyl)cyclopropane-1-carboxylic acid |
| ANLO-013 | 1058156-88-9 | benzyl (1-(((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinolin-7-yl)oxy)methyl)cyclopropyl)carbamate |
Frequently asked questions
What are the approved indications of Anlotinib Dihydrochloride?
Approved indications include: 肺泡软组织肉瘤, 肝细胞癌, 子宫内膜癌, 甲状腺瘤, 甲状腺髓样癌, 小细胞肺癌, 肉瘤, 非小细胞肺癌.
When does the Anlotinib Dihydrochloride patent expire?
No public expiry year is available for Anlotinib Dihydrochloride yet; this page updates once verified.
How many synthesis routes are recorded for Anlotinib Dihydrochloride?
1 synthesis routes are recorded; the shortest is 11 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Anlotinib Dihydrochloride intermediates?
All intermediates in Anlotinib Dihydrochloride routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Anlotinib Dihydrochloride intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24