阿利沙坦酯
Tier C — Watch / tradeAllisartan Isoproxil
Targets：AT1
Brand：信立坦
Indications (approved)：高血压
Regional status
Synthetic routes & intermediates3 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| ALIS-003 | 947331-10-4 | ((isopropoxycarbonyl)oxy)methyl 2-butyl-4-chloro-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carboxylate |
| ALIS-004 | 35180-01-9 | 2-butyl-4-chloro-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carbaldehyde |
| ALIS-005 | 947331-22-8 | ((isopropoxycarbonyl)oxy)methyl 2-butyl-4-chloro-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carboxylate |
| ALIS-001 | 124750-99-8 | 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazole-5-carboxylic acid |
| ALIS-002 | 124750-92-1 | 2-butyl-4-chloro-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carboxylic acid |
| Code | CAS No. | Intermediate |
|---|---|---|
| ALIS-001 | 124750-99-8 | 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazole-5-carboxylic acid |
| ALIS-003 | 947331-10-4 | ((isopropoxycarbonyl)oxy)methyl 2-butyl-4-chloro-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carboxylate |
| ALIS-004 | 35180-01-9 | 2-butyl-4-chloro-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carbaldehyde |
| ALIS-005 | 947331-22-8 | ((isopropoxycarbonyl)oxy)methyl 2-butyl-4-chloro-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carboxylate |
| ALIS-006 | 124751-00-4 | (2-butyl-4-chloro-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazol-5-yl)methanol |
| ALIS-007 | 120568-18-5 | 2-butyl-5-chloro-3-[[4-[2-(1-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carbaldehyde |
| Code | CAS No. | Intermediate |
|---|---|---|
| ALIS-004 | 35180-01-9 | 2-butyl-4-chloro-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carbaldehyde |
| ALIS-008 | 114772-54-2 | 4'-(bromomethyl)-[1,1'-biphenyl]-2-carbonitrile |
| ALIS-009 | 83857-96-9 | 2-butyl-4-chloro-1H-imidazole-5-carbaldehyde |
| ALIS-010 | 124750-67-0 | 4'-((2-butyl-4-chloro-5-formyl-1H-imidazol-1-yl)methyl)-[1,1'-biphenyl]-2-carbonitrile |
| ALIS-011 | - | 2-butyl-4-chloro-1-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carboxylic acid |
| ALIS-012 | - | ((isopropoxycarbonyl)oxy)methyl 2-butyl-4-chloro-1-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carboxylate |
Frequently asked questions
What are the approved indications of Allisartan Isoproxil?
Approved indications include: 高血压.
When does the Allisartan Isoproxil patent expire?
No public expiry year is available for Allisartan Isoproxil yet; this page updates once verified.
How many synthesis routes are recorded for Allisartan Isoproxil?
3 synthesis routes are recorded; the shortest is 4 steps with 0.436 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Allisartan Isoproxil intermediates?
All intermediates in Allisartan Isoproxil routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Allisartan Isoproxil intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24