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CAS 100361-18-0
7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
Codes：ZABO-012
Application context (from source-drug indications)
慢性阻塞性肺疾病Zabofloxacin Hydrochloride社区获得性肺炎Zabofloxacin Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Zabofloxacin HydrochlorideZabofloxacin Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-benzyl 3-ethyl 4-oxopyrrolidine-1,3-dicarboxylate→1-benzyl 3-ethyl 3-(hydroxymethyl)-4-oxopyrrolidine-1,3-dicarboxylate→(Z)-1-benzyl 3-ethyl 3-(hydroxymethyl)-4-(methoxyimino)pyrrolidine-1,3-dicarboxylate→(Z)-1-benzyl 3-ethyl 4-(methoxyimino)-3-(((methylsulfonyl)oxy)methyl)pyrrolidine-1,3-dicarboxylate→(E)-benzyl 3-(hydroxymethyl)-4-(methoxyimino)-3-(((methylsulfonyl)oxy)methyl)pyrrolidine-1-carboxylate→(E)-benzyl 3-(azidomethyl)-3-(hydroxymethyl)-4-(methoxyimino)pyrrolidine-1-carboxylate→(E)-benzyl 3-(azidomethyl)-4-(methoxyimino)-3-(((methylsulfonyl)oxy)methyl)pyrrolidine-1-carboxylate→(E)-benzyl 3-(aminomethyl)-4-(methoxyimino)-3-(((methylsulfonyl)oxy)methyl)pyrrolidine-1-carboxylate→(E)-benzyl 8-(methoxyimino)-2,6-diazaspiro[3.4]octane-6-carboxylate→(E)-6-benzyl 2-tert-butyl 8-(methoxyimino)-2,6-diazaspiro[3.4]octane-2,6-dicarboxylate→(E)-tert-butyl 8-(methoxyimino)-2,6-diazaspiro[3.4]octane-2-carboxylate→7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid→(E)-7-(2-(tert-butoxycarbonyl)-8-(methoxyimino)-2,6-diazaspiro[3.4]octan-6-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.