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CAS 106649-02-9
1-Methyl-1H-indazole-3-carbonyl chloride
Codes: Granisetron-002
Application context (from source-drug indications)
Chemotherapy-induced nausea and vomitingGranisetronNauseaGranisetron呕吐Granisetron手术后恶心呕吐GranisetronPostoperative painGranisetronGastroparesisGranisetron
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Granisetron | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-Methylindazole-3-carboxylic acid→1-Methyl-1H-indazole-3-carbonyl chloride→endo-9-Methyl-9-azabicyclo[3.3.1]nonan-3-amine
2,3-Indolinedione→Iodomethane→1-Methyl-1H-indole-2,3-dione→3,3-Dimethoxy-1-methyl-1,3-dihydro-2H-indol-2-one→1-Methylindazole-3-carboxylic acid→1-Methyl-1H-indazole-3-carbonyl chloride→endo-9-Methyl-9-azabicyclo[3.3.1]nonan-3-amine→Glutaraldehyde→Methanamine hydrochloride→1,3-Acetonedicarboxylic acid→9-Methyl-9-azabicyclo[3.3.1]nonan-3-one→Hydroxylamine hydrochloride→N-Hydroxy-9-methyl-9-azabicyclo[3.3.1]nonan-3-imine→1-Methyl-2,3-dihydro-1H-indole
Intermediates available on this site
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