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CAS 112764-00-8
(R)-3-hexyl-4-hydroxy-6-undecyl-5,6-dihydro-2H-pyran-2-one
Codes: ORLI-065
Application context (from source-drug indications)
ObesityOrlistatI型高脂蛋白血症OrlistatHypertriglyceridaemiaOrlistat女性不孕OrlistatDiabetesOrlistatObstructive sleep apnoea syndromeOrlistat
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Orlistat | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(3S,4S)-4-((R)-2-(benzyloxy)tridecyl)-3-hexyloxetan-2-one→(3S,4S)-3-hexyl-4-((R)-2-hydroxytridecyl)oxetan-2-one→(S)-2-formamido-4-methylpentanoic acid→methyl 3-oxotetradecanoate→methyl (R)-3-hydroxytetradecanoate→2-bromooctanoyl bromide→(3R)-methyl 3-((2-bromooctanoyl)oxy)tetradecanoate→(R)-3-hexyl-4-hydroxy-6-undecyl-5,6-dihydro-2H-pyran-2-one→(3S,4S,6R)-3-hexyl-4-hydroxy-6-undecyltetrahydro-2H-pyran-2-one→(S)-1-phenylethanamine (2S,3S,5R)-5-(benzyloxy)-2-hexyl-3-hydroxyhexadecanoate
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