CAS 1231755-15-9

[(2,2,2-Trifluoroethylcarbamoyl)methyl]carbamic acid tert-butyl ester

Codes: (XVIIIb)700647-1-b

Application context (from source-drug indications)

蠕形螨性睑缘炎Lotilaner螨虫感染Lotilaner莱姆病LotilanerRosaceaLotilaner睑板腺功能障碍Lotilaner

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
Lotilaner	Tier C — Watch / trade	-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

LotilanerOptimised routesteps: 3total yield: /

2-Amino-N-(2,2,2-trifluoroethyl)acetamide hydrochloride→2,5-Dioxo-3-oxazolidinecarboxylic acid 1,1-dimethylethyl ester→2-(Benzyloxycarbonylamino)acetic acid→2-((tert-Butoxycarbonyl)amino)acetic acid→2-Amino-1,1,1-trifluoroethane hydrochloride→2-Amino-1,1,1-trifluoroethane→Benzyl [2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]carbamate→[(2,2,2-Trifluoroethylcarbamoyl)methyl]carbamic acid tert-butyl ester→2-Chloranylethanoyl chloride→2-Chloro-N-(2,2,2-trifluoroethyl)acetamide→(N-Benzylaminomethyl)benzene→2-(Dibenzylamino)-N-(2,2,2-trifluoroethyl)acetamide

Intermediates available on this site

Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.

Supplier	Product	Price band	MOQ	Lead time	Qualifications
Unibest Nantong cGMP Site	2-bromo-3-methyl-5-acetylthiophene Pharmaceutical Intermediates	On request	On request	On request	—
Unibest Taizhou GMP-like Site	methyl 5-acetyl-3-methylthiophene-2-carboxylate Pharmaceutical Intermediates	On request	On request	On request	—
Qualified Partner — East China API Works	5-acetyl-3-methyl-2-Thiophenecarboxylic acid Pharmaceutical Intermediates	On request	On request	On request	—

This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.