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CAS 1267610-26-3
1-(4-aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one
Codes：APIX-030
Application context (from source-drug indications)
肺栓塞阿哌沙班静脉血栓形成阿哌沙班Paget-Schroetter综合征阿哌沙班静脉血栓栓塞阿哌沙班血栓形成阿哌沙班栓塞阿哌沙班
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 阿哌沙班Apixaban | Tier A — Act now | 2028 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
ethyl (Z)-2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate→ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate→3-morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one→4-nitroaniline→1-(4-nitrophenyl)piperidin-2-one→5-chloropentanoyl chloride→3-morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one→1-(4-aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one
Intermediates available on this site
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| Supplier | Product | Price band | MOQ | Lead time | Qualifications |
|---|---|---|---|---|---|
| Unibest Taizhou GMP-like Site | 1-(4-Aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
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