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CAS 128573-54-6

(2R,3E)-2-Hydroxy-4-phenylbut-3-enoic acid

Codes:Enalapril-052

Application context (from source-drug indications)

心脏和血管疾病阿托伐他汀/氢氯噻嗪/阿司匹林/依那普利高血压阿托伐他汀/氢氯噻嗪/阿司匹林/依那普利高脂血症阿托伐他汀/氢氯噻嗪/阿司匹林/依那普利心脏病阿托伐他汀/氢氯噻嗪/阿司匹林/依那普利原发性高血压马来酸依那普利/叶酸

Source drugs (routes using this intermediate)

DrugTierExpiry
阿托伐他汀/氢氯噻嗪/阿司匹林/依那普利Atorvastatin/Hydrochlorothiazide/Aspirin/EnalaprilTier C — Watch / trade-
马来酸依那普利/叶酸Enalapril Maleate/Folic AcidTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

阿托伐他汀/氢氯噻嗪/阿司匹林/依那普利优化路线steps: 4total yield: 3.28g(Enalapril-054)
Bitter almond→2-Oxopropionic acid→Potassium (3E)-2-oxo-4-phenylbut-3-enoate→(2R,3E)-2-Hydroxy-4-phenylbut-3-enoic acid→2(R)-Hydroxy-4-phenylbutyric acid→Ethyl (R)-(-)-2-hydroxy-4-phenylbutyrate
马来酸依那普利/叶酸优化路线steps: 4total yield: 3.28g(Enalapril-054)
Bitter almond→2-Oxopropionic acid→Potassium (3E)-2-oxo-4-phenylbut-3-enoate→(2R,3E)-2-Hydroxy-4-phenylbut-3-enoic acid→2(R)-Hydroxy-4-phenylbutyric acid→Ethyl (R)-(-)-2-hydroxy-4-phenylbutyrate

Intermediates available on this site

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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.