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CAS 1289942-55-7

4-((1-((4-cyano-3-(trifluoromethyl)phenyl)amino)-2-methyl-1-oxopropan-2-yl)amino)-2-fluoro-N-methylbenzamide

Codes:ENZA-014

Application context (from source-drug indications)

激素敏感性前列腺肿瘤恩扎卢胺去势抵抗性前列腺肿瘤恩扎卢胺前列腺癌恩扎卢胺

Source drugs (routes using this intermediate)

DrugTierExpiry
恩扎卢胺EnzalutamideTier A — Act now2027

Position in synthesis routes (up/downstream chain)

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恩扎卢胺优化路线steps: 2total yield: 4 mg
2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid→4-amino-2-(trifluoromethyl)benzonitrile→4-((1-((4-cyano-3-(trifluoromethyl)phenyl)amino)-2-methyl-1-oxopropan-2-yl)amino)-2-fluoro-N-methylbenzamide

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