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CAS 1289942-66-0
2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid
Codes：ENZA-011
Application context (from source-drug indications)
激素敏感性前列腺肿瘤恩扎卢胺去势抵抗性前列腺肿瘤恩扎卢胺前列腺癌恩扎卢胺
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 恩扎卢胺Enzalutamide | Tier A — Act now | 2027 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-isothiocyanato-2-(trifluoromethyl)benzonitrile→4-bromo-2-fluorobenzoic acid→4-bromo-2-fluoro-N-methylbenzamide→2-amino-2-methylpropanoic acid→2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid→methyl 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate
2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid→4-amino-2-(trifluoromethyl)benzonitrile→4-((1-((4-cyano-3-(trifluoromethyl)phenyl)amino)-2-methyl-1-oxopropan-2-yl)amino)-2-fluoro-N-methylbenzamide
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