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CAS 1297537-35-9
2-chloro-4-(1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-5-yl)benzonitrile
Codes：ODM-201-003
Application context (from source-drug indications)
激素敏感性前列腺肿瘤达罗他胺去势敏感性前列腺肿瘤达罗他胺前列腺癌达罗他胺去势抵抗性前列腺肿瘤达罗他胺
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 达罗他胺Darolutamide | Tier B — Position early | 2031 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-bromo-2-chlorobenzonitrile→1-(tetrahydro-2H-pyran-2-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole→2-chloro-4-(1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-5-yl)benzonitrile→2-chloro-4-(1H-pyrazol-3-yl)benzonitrile hydrochloride→2-chloro-4-(1H-pyrazol-3-yl)benzonitrile→tert-butyl (S)-(1-hydroxypropan-2-yl)carbamate→(S)-4-(1-(2-aminopropyl)-1H-pyrazol-3-yl)-2-chlorobenzonitrile→5-acetyl-1H-pyrazole-3-carboxylic acid→(S)-5-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1H-pyrazole-3-carboxamide
Intermediates available on this site
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| Supplier | Product | Price band | MOQ | Lead time | Qualifications |
|---|---|---|---|---|---|
| Qualified Partner — East China API Works | 4-Bromo-2-chlorobenzonitrile Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.