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CAS 133860-61-4
4-nitrophenyl 3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoate
Codes：PEGL-008
Application context (from source-drug indications)
二型糖尿病聚乙二醇洛塞那肽肥胖症聚乙二醇洛塞那肽子宫内膜增生聚乙二醇洛塞那肽
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 聚乙二醇洛塞那肽PEG-Loxenatide | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-(2-methoxyethoxy)ethan-1-ol→2-(2-methoxyethoxy)ethyl carbonochloridate→2,5-dioxopyrrolidin-1-yl (2-(2-methoxyethoxy)ethyl) carbonate→15-(((2-(2-methoxyethoxy)ethoxy)carbonyl)amino)-9-oxo-2,5,8-trioxa-10-azahexadecan-16-oic acid→2,5-dioxopyrrolidin-1-yl 15-(((2-(2-methoxyethoxy)ethoxy)carbonyl)amino)-9-oxo-2,5,8-trioxa-10-azahexadecan-16-oate→ethane-1,2-diamine→bis(2-(2-methoxyethoxy)ethyl) (6-((2-aminoethyl)amino)-6-oxohexane-1,5-diyl)dicarbamate→4-nitrophenyl 3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoate→bis(2-(2-methoxyethoxy)ethyl) (6-((2-(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido)ethyl)amino)-6-oxohexane-1,5-diyl)dicarbamate
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