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CAS 1353553-07-7
2-chloro-4-(3-nitrophenoxy)thieno[3,2-d]pyrimidine
Codes：OLMU-006
Application context (from source-drug indications)
非小细胞肺癌奥莫替尼
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 奥莫替尼Olmutinib | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
Methyl 3-aminothiophene-2-carboxylate→Urea→Thieno[3,2-d]pyrimidine-2,4(1H,3H)-dione→2,4-dichlorothieno[3,2-d]pyrimidine→3-nitrophenol→2-chloro-4-(3-nitrophenoxy)thieno[3,2-d]pyrimidine→4-(4-methylpiperazin-1-yl)aniline→N-(4-(4-methylpiperazin-1-yl)phenyl)-4-(3-nitrophenoxy)thieno[3,2-d]pyrimidin-2-amine→4-(3-aminophenoxy)-N-(4-(4-methylpiperazin-1-yl)phenyl)thieno[3,2-d]pyrimidin-2-amine→Acryloyl chloride
Intermediates available on this site
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