奥莫替尼
Tier C — Watch / tradeOlmutinib
Targets：EGFR T790M
Brand：Olita
Indications (approved)：非小细胞肺癌
Regional status
Synthetic routes & intermediates2 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| OLMU-001 | 22288-78-4 | Methyl 3-aminothiophene-2-carboxylate |
| OLMU-002 | 57-13-6 | Urea |
| OLMU-003 | 16233-51-5 | Thieno[3,2-d]pyrimidine-2,4(1H,3H)-dione |
| OLMU-004 | 16234-14-3 | 2,4-dichlorothieno[3,2-d]pyrimidine |
| OLMU-005 | 554-84-7 | 3-nitrophenol |
| OLMU-006 | 1353553-07-7 | 2-chloro-4-(3-nitrophenoxy)thieno[3,2-d]pyrimidine |
| OLMU-007 | 16153-81-4 | 4-(4-methylpiperazin-1-yl)aniline |
| OLMU-008 | 1353553-08-8 | N-(4-(4-methylpiperazin-1-yl)phenyl)-4-(3-nitrophenoxy)thieno[3,2-d]pyrimidin-2-amine |
| OLMU-009 | 1353553-09-9 | 4-(3-aminophenoxy)-N-(4-(4-methylpiperazin-1-yl)phenyl)thieno[3,2-d]pyrimidin-2-amine |
| OLMU-010 | 814-68-6Available | Acryloyl chloride |
| Code | CAS No. | Intermediate |
|---|---|---|
| OLMU-004 | 16234-14-3 | 2,4-dichlorothieno[3,2-d]pyrimidine |
| OLMU-007 | 16153-81-4 | 4-(4-methylpiperazin-1-yl)aniline |
| OLMU-011 | 13040-21-6 | N-(3-hydroxyphenyl)acrylamide |
| OLMU-012 | 2095840-80-3 | N-(3-((2-chlorothieno[3,2-d]pyrimidin-4-yl)oxy)phenyl)acrylamide |
Frequently asked questions
What are the approved indications of Olmutinib?
Approved indications include: 非小细胞肺癌.
When does the Olmutinib patent expire?
No public expiry year is available for Olmutinib yet; this page updates once verified.
How many synthesis routes are recorded for Olmutinib?
2 synthesis routes are recorded; the shortest is 2 steps with 50.6 g (Olmutinib) total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Olmutinib intermediates?
1 intermediate CAS of Olmutinib are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Olmutinib intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24