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CAS 13726-52-8
N-(4-Aminobenzoyl)-L-glutamic acid diethyl diester
Codes：Folic Acid-006
Application context (from source-drug indications)
原发性高血压马来酸依那普利/叶酸巨幼红细胞性贫血叶酸叶酸缺乏叶酸神经管缺损叶酸贫血叶酸热潮红叶酸高同型半胱氨酸血症叶酸
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Enalapril Maleate/Folic AcidEnalapril Maleate/Folic Acid | Tier C — Watch / trade | - |
| Folic AcidFolic Acid | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-(2-Amino-4-oxo-3,4-dihydropteridin-6-ylmethyl)pyridinium iodide→2-Amino-6-methyl-3,4,5,8-tetrahydropteridin-4-one→2-Amino-6-methylpteridin-4(3H)-one→2-Amino-6-(chloromethyl)pteridin-4(3H)-one→2-Amino-6-(bromomethyl)pteridin-4(3H)-one→N-(4-Aminobenzoyl)-L-glutamic acid diethyl diester→N-[4-(2-Amino-4-oxo-1,4-dihydropteridin-6-ylmethylamino)benzoyl]-L-glutamic acid diethyl diester
2,3-Dihydroxy-2-propenal→N-(4-Aminobenzoyl)-L-glutamic acid diethyl diester→N-[4-[2,3-Dihydroxy-2-propenylideneamino]benzoyl]-L-glutamic acid diethyl diester→2,5,6-Triaminopyrimidin-4(5H)-one
N-(4-Aminobenzoyl)-L-glutamic acid→N-(4-Aminobenzoyl)-L-glutamic acid diethyl diester→2,3-Dibromopropanal→N-[4-(2,3-Dibromopropylideneamino)benzoyl]-L-glutamic acid diethyl diester→2,5,6-Triaminopyrimidin-4(5H)-one→N-[4-(2-Amino-4-oxo-1,4-dihydropteridin-6-ylmethylamino)benzoyl]-L-glutamic acid diethyl diester
1-(2-Amino-4-oxo-3,4-dihydropteridin-6-ylmethyl)pyridinium iodide→2-Amino-6-methyl-3,4,5,8-tetrahydropteridin-4-one→2-Amino-6-methylpteridin-4(3H)-one→2-Amino-6-(chloromethyl)pteridin-4(3H)-one→2-Amino-6-(bromomethyl)pteridin-4(3H)-one→N-(4-Aminobenzoyl)-L-glutamic acid diethyl diester→N-[4-(2-Amino-4-oxo-1,4-dihydropteridin-6-ylmethylamino)benzoyl]-L-glutamic acid diethyl diester
2,3-Dihydroxy-2-propenal→N-(4-Aminobenzoyl)-L-glutamic acid diethyl diester→N-[4-[2,3-Dihydroxy-2-propenylideneamino]benzoyl]-L-glutamic acid diethyl diester→2,5,6-Triaminopyrimidin-4(5H)-one
N-(4-Aminobenzoyl)-L-glutamic acid→N-(4-Aminobenzoyl)-L-glutamic acid diethyl diester→2,3-Dibromopropanal→N-[4-(2,3-Dibromopropylideneamino)benzoyl]-L-glutamic acid diethyl diester→2,5,6-Triaminopyrimidin-4(5H)-one→N-[4-(2-Amino-4-oxo-1,4-dihydropteridin-6-ylmethylamino)benzoyl]-L-glutamic acid diethyl diester
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