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CAS 1430836-78-4
2,4-di-tert-butyl-5-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl ethyl carbonate
Codes：IVAC-016
Application context (from source-drug indications)
囊性纤维化艾伐卡托慢性支气管炎艾伐卡托慢性阻塞性肺疾病艾伐卡托鼻窦炎艾伐卡托
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 艾伐卡托Ivacaftor | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2,4-di-tert-butylphenol→ethyl carbonochloridate→2,4-di-tert-butylphenyl ethyl carbonate→2,4-di-tert-butyl-5-nitrophenyl ethyl carbonate→5-amino-2,4-di-tert-butylphenyl ethyl carbonate→4-oxo-1,4-dihydroquinoline-3-carbonyl chloride→2,4-di-tert-butyl-5-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl ethyl carbonate
Intermediates available on this site
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