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CAS 1450983-42-2

(S)-(1-(4-((3-chloro-4-methoxybenzyl)amino)pyrimidin-2-yl)pyrrolidin-2-yl)methanol

CodesAVAN-020

Application context (from source-drug indications)

勃起功能障碍阿伐那非

Source drugs (routes using this intermediate)

DrugTierExpiry
阿伐那非AvanafilTier C — Watch / trade2028

Position in synthesis routes (up/downstream chain)

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阿伐那非优化路线steps: 3total yield: 1.96 g
(S)-pyrrolidin-2-ylmethanol4-(bromomethyl)-2-chloro-1-methoxybenzene4-aminopyrimidin-2(1H)-one4-((3-chloro-4-methoxybenzyl)amino)pyrimidin-2(1H)-one(S)-(1-(4-((3-chloro-4-methoxybenzyl)amino)pyrimidin-2-yl)pyrrolidin-2-yl)methanolN-(pyrimidin-2-ylmethyl)formamide

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