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CAS 1451396-66-9
(6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12bS)-8b-(2-bromoacetyl)-10-cyclohexyl-7-hydroxy-6a,8a-dimethyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one
Codes: CICL-012
Application context (from source-drug indications)
AsthmaCiclesonidePerennial allergic rhinitisCiclesonideSeasonal allergic rhinitisCiclesonideAllergic rhinitisCiclesonide支气管肺发育不良CiclesonideCOVID-19Ciclesonide
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Ciclesonide | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
cyclohexanecarbaldehyde→(8S,11S,13S,14S,16R,17S)-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-13-methyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one→(6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12bS)-8b-(2-bromoacetyl)-10-cyclohexyl-7-hydroxy-6a,8a-dimethyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one→sodium isobutyrate
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