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CAS 147189-99-9
tert-Butyl 4-(3,4-dichlorophenyl)-4-oxobutanoate
Codes：Sertraline Hydrochloride-103
Application context (from source-drug indications)
强迫性障碍枸橼酸舍曲林
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 枸橼酸舍曲林Sertraline Citrate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-(3,4-Dichlorophenyl)-4-oxobutanoic acid→Phenyllithium→4(S)-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-one→tert-Butyl 4-(3,4-dichlorophenyl)-4-oxobutanoate→tert-Butyl (4R)-4-(3,4-dichlorophenyl)-4-hydroxybutanoate→tert-Butyl (4R)-4-(3,4-dichlorophenyl)-4-[(methanesulfonyl)oxy]butanoate→tert-Butyl (4R)-4-(3,4-dichlorophenyl)-4-phenylbutanoate
Intermediates available on this site
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