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CAS 147190-01-0

tert-Butyl (4R)-4-(3,4-dichlorophenyl)-4-[(methanesulfonyl)oxy]butanoate

Codes:Sertraline Hydrochloride-102

Application context (from source-drug indications)

强迫性障碍枸橼酸舍曲林

Source drugs (routes using this intermediate)

DrugTierExpiry
枸橼酸舍曲林Sertraline CitrateTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

枸橼酸舍曲林优化路线steps: 5total yield: /
4-(3,4-Dichlorophenyl)-4-oxobutanoic acid→Phenyllithium→4(S)-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-one→tert-Butyl 4-(3,4-dichlorophenyl)-4-oxobutanoate→tert-Butyl (4R)-4-(3,4-dichlorophenyl)-4-hydroxybutanoate→tert-Butyl (4R)-4-(3,4-dichlorophenyl)-4-[(methanesulfonyl)oxy]butanoate→tert-Butyl (4R)-4-(3,4-dichlorophenyl)-4-phenylbutanoate

Intermediates available on this site

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