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CAS 1518795-13-5
4-chloro-3-(4-ethoxybenzyl)benzyl acetate
Codes：ERTU-033
Application context (from source-drug indications)
二型糖尿病艾托格列净二尖瓣闭锁不全艾托格列净左心室功能不全艾托格列净心脏衰竭艾托格列净动脉粥样硬化艾托格列净胰岛素抵抗艾托格列净
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 艾托格列净Ertugliflozin | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(3aS,4S,6R,6aS)-6-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-ol→tert-butyl(((3aS,4R,6R,6aS)-6-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)oxy)dimethylsilane→(R)-1-((3aS,4R,6R,6aS)-6-((tert-butyldimethylsilyl)oxy)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)ethane-1,2-diol→(3aS,4S,6R,6aS)-6-((tert-butyldimethylsilyl)oxy)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole-4-carbaldehyde→2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1,3-dithiane→(R)-((3aS,4R,6R,6aS)-6-((tert-butyldimethylsilyl)oxy)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)(2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1,3-dithian-2-yl)methanol→(3aS,4S,6R,6aS)-6-((R)-(2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1,3-dithian-2-yl)(hydroxy)methyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-ol→(3aS,6R,6aS)-6-((R)-(2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1,3-dithian-2-yl)(hydroxy)methyl)-3a-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-ol→(1R,2R)-1-((S)-5,5-bis(hydroxymethyl)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-(2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1,3-dithian-2-yl)ethane-1,2-diol→2-chloro-5-methylbenzoic acid→ethoxybenzene→(2-chloro-5-methylphenyl)(4-ethoxyphenyl)methanone→(5-(bromomethyl)-2-chlorophenyl)(4-ethoxyphenyl)methanone→4-(bromomethyl)-1-chloro-2-(4-ethoxybenzyl)benzene→4-chloro-3-(4-ethoxybenzyl)benzyl acetate→(4-chloro-3-(4-ethoxybenzyl)phenyl)methanol→4-chloro-3-(4-ethoxybenzyl)benzaldehyde→propane-1,3-dithiol
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications |
|---|---|---|---|---|---|
| Unibest Taizhou GMP-like Site | 2-((benzyloxy)(4-ethoxyphenyl)methyl)-4-bromo-1-chlorobenzene Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Qualified Partner — East China API Works | (2R, 3S.4S)-2, 3, 4-tris(benzyloxy)-4-((R)-4-((benzyloxy)meth yl)-2, 2-dimeth yl-1, 3- dioxolan-4-yl)-1-(4-methylDiDerazin-1-yl)butan-1-one Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
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