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CAS 1620210-75-4
methyl (E)-2-chloro-3-(tosyloxy)acrylate
Codes: ETOR-022
Application context (from source-drug indications)
OsteoarthritisEtoricoxib痛风性关节炎EtoricoxibDysmenorrhoeaEtoricoxibRheumatoid arthritisEtoricoxibAnkylosing spondylitisEtoricoxibParkinson's diseaseEtoricoxib
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Etoricoxib | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-(6-methylpyridin-3-yl)-2-(4-(methylsulfonyl)phenyl)ethan-1-one→methyl (E)-2-chloro-3-(tosyloxy)acrylate→3-chloro-6-(6-methylpyridin-3-yl)-5-(4-(methylsulfonyl)phenyl)-2H-pyran-2-one→5-chloro-6'-methyl-3-(4-(methylsulfonyl)phenyl)-[2,3'-bipyridin]-6-ol→5-chloro-6'-methyl-3-(4-(methylsulfonyl)phenyl)-[2,3'-bipyridin]-6-yl 4-methylbenzenesulfonate
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