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CAS 1808952-22-8

(R)-1-(3-(2-cyano-5-fluorobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidine-3-carboxamide

CodesTREL-018

Application context (from source-drug indications)

二型糖尿病琥珀酸曲格列汀糖尿病琥珀酸曲格列汀

Source drugs (routes using this intermediate)

DrugTierExpiry
琥珀酸曲格列汀Trelagliptin SuccinateTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

琥珀酸曲格列汀优化路线steps: 5total yield: 1.2 g
2-((6-chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrilesuccinic acidnicotinamide1,4,5,6-tetrahydropyridine-3-carboxamide(R)-piperidine-3-carboxamide 4-methylbenzenesulfonate(R)-1-(3-(2-cyano-5-fluorobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidine-3-carboxamide

Intermediates available on this site

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