琥珀酸曲格列汀
Tier C — Watch / tradeTrelagliptin Succinate
Targets：DPP4
Brand：Zafatek
Indications (approved)：二型糖尿病
Regional status
Synthetic routes & intermediates3 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| TREL-001 | 452-63-1 | 1-bromo-4-fluoro-2-methylbenzene |
| TREL-002 | 147754-12-9 | 4-fluoro-2-methylbenzonitrile |
| TREL-003 | 421552-12-7Available | 2-(bromomethyl)-4-fluorobenzonitrile |
| TREL-004 | 4318-56-3Available | 6-chloro-3-methylpyrimidine-2,4(1H,3H)-dione |
| TREL-005 | 865759-24-6 | 2-((6-chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile |
| TREL-006 | 127294-73-9 | (R)-piperidin-3-amine |
| TREL-007 | 110-15-6 | succinic acid |
| TREL-008 | 16682-12-5 | (R)-2,5-diaminopentanoic acid hydrochloride |
| TREL-009 | 205598-55-6 | (R)-methyl 2,5-diaminopentanoate |
| TREL-010 | 406216-02-2 | (R)-3-aminopiperidin-2-one hydrochloride |
| TREL-011 | 127294-73-9 | (R)-piperidin-3-amine |
| Code | CAS No. | Intermediate |
|---|---|---|
| TREL-003 | 421552-12-7Available | 2-(bromomethyl)-4-fluorobenzonitrile |
| TREL-004 | 4318-56-3Available | 6-chloro-3-methylpyrimidine-2,4(1H,3H)-dione |
| TREL-005 | 865759-24-6 | 2-((6-chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile |
| TREL-006 | 127294-73-9 | (R)-piperidin-3-amine |
| TREL-012 | 886588-61-0 | (R)-2-(piperidin-3-yl)isoindoline-1,3-dione |
| TREL-013 | 1430222-10-8 | (R)-2-((6-(3-(1,3-dioxoisoindolin-2-yl)piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile |
| TREL-014 | 85-44-9Available | isobenzofuran-1,3-dione |
| Code | CAS No. | Intermediate |
|---|---|---|
| TREL-005 | 865759-24-6 | 2-((6-chloro-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile |
| TREL-007 | 110-15-6 | succinic acid |
| TREL-015 | 98-92-0 | nicotinamide |
| TREL-016 | 7032-11-3 | 1,4,5,6-tetrahydropyridine-3-carboxamide |
| TREL-017 | - | (R)-piperidine-3-carboxamide 4-methylbenzenesulfonate |
| TREL-018 | 1808952-22-8 | (R)-1-(3-(2-cyano-5-fluorobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidine-3-carboxamide |
Frequently asked questions
What are the approved indications of Trelagliptin Succinate?
Approved indications include: 二型糖尿病.
When does the Trelagliptin Succinate patent expire?
No public expiry year is available for Trelagliptin Succinate yet; this page updates once verified.
How many synthesis routes are recorded for Trelagliptin Succinate?
3 synthesis routes are recorded; the shortest is 4 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Trelagliptin Succinate intermediates?
3 intermediate CAS of Trelagliptin Succinate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Trelagliptin Succinate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24