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CAS 18531-99-2

[1,1'-binaphthalene]-2,2'-diol

Codes: ESOME-017

Application context (from source-drug indications)

HeartburnEsomeprazole Magnesium HydrateGastro-oesophageal reflux diseaseEsomeprazole Magnesium HydrateDuodenal ulcerEsomeprazole Magnesium HydrateGastric ulcerEsomeprazole Magnesium HydratePeptic oesophagitisEsomeprazole Magnesium HydrateHelicobacter pylori infectionEsomeprazole Magnesium Hydrate

Source drugs (routes using this intermediate)

DrugTierExpiry
Esomeprazole Magnesium HydrateTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Esomeprazole Magnesium HydrateOptimised routesteps: 3total yield: 31.60 g
5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole→sodium (S)-5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide→[1,1'-binaphthalene]-2,2'-diol→[1,1'-binaphthalene]-2,2'-diol compound with 5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole (1:1)→isopropyl acetate

Intermediates available on this site

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