CAS 186381-39-5

Methyl exo,exo-3-(4-iodophenyl)-8-(3-[[(4-methylphenyl)sulfonyl]oxy]propyl)-8-azabicyclo[3.2.1]octane-2-carboxylateMethyl (1R,2S,3S,5S)-3-(4-iodophenyl)-8-(3-[[(4-methylphenyl)sulfonyl]oxy]propyl)-8-azabicyclo[3.2.1]octane-2-carboxylate

Codes：18F-FP-CIT-006

Application context (from source-drug indications)

帕金森病18F-FP-CIT

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
18F-FP-CIT18F-FP-CIT	Tier C — Watch / trade	-

Position in synthesis routes (up/downstream chain)

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18F-FP-CIT优化路线steps: 2total yield: /

Methyl exo,exo-3-(4-iodophenyl)-8-(3-[[(4-methylphenyl)sulfonyl]oxy]propyl)-8-azabicyclo[3.2.1]octane-2-carboxylate→Methyl exo,exo-3-(4-iodophenyl)spiro[bicyclo[3.2.1]octane-8,1'-azetidinium]-2-carboxylate

18F-FP-CIT优化路线steps: 1total yield: 4.082mg(18F-FP-CIT (Free))

Methyl (1R,2S,3S,5S)-3-(4-iodophenyl)-8-[3-[(methylsulfonyl)oxy]propyl]-8-azabicyclo[3.2.1]octane-2-carboxylate→Methyl (1R,2S,3S,5S)-3-(4-iodophenyl)-8-(3-[[(4-methylphenyl)sulfonyl]oxy]propyl)-8-azabicyclo[3.2.1]octane-2-carboxylate

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