18F-FP-CIT

Tier C — Watch / trade

18F-FP-CIT

FutureChem Co Ltd

Originator

2008

First approval

Expiry (public)

No sales data

Peak sales

放射性产品

Type

Targets：DAT

Brand：PDvue

Indications (approved)：帕金森病

Regional status

China

Japan

Synthetic routes & intermediates4 routes

Originator routes × 0Optimised (non-patent) × 4Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OptimisedRoute 1Steps 4 · Total yield /

Synthetic routes & intermediates Route 1

Code	CAS No.	Intermediate
18F-FP-CIT-001	627-18-9	Trimethylene bromohydrin
18F-FP-CIT-002	81055-36-9	3-Bromopropyl 4-methylbenzenesulfonate
18F-FP-CIT-003	108607-98-3	1-Bromo-3-[18F]fluoropropane
18F-FP-CIT-004	915154-86-8	3-[18F]Fluoropropyl trifluoromethanesulfonate
18F-FP-CIT-005	136794-87-1	Methyl (1R,2S,3S,5S)-3-(4-iodophenyl)-8-azabicyclo[3.2.1]octane-2-carboxylate

OptimisedRoute 2Steps 2 · Total yield /

Synthetic routes & intermediates Route 2

Code	CAS No.	Intermediate
18F-FP-CIT-006	186381-39-5	Methyl exo,exo-3-(4-iodophenyl)-8-(3-[[(4-methylphenyl)sulfonyl]oxy]propyl)-8-azabicyclo[3.2.1]octane-2-carboxylate
18F-FP-CIT-007	1372611-82-9	Methyl exo,exo-3-(4-iodophenyl)spiro[bicyclo[3.2.1]octane-8,1'-azetidinium]-2-carboxylate

OptimisedRoute 3Steps 2 · Total yield 13.15-11.14mg(18F-FP-CIT (Free))

Synthetic routes & intermediates Route 3

Code	CAS No.	Intermediate
18F-FP-CIT-008	109-64-8	1,3-Dibromopropane
18F-FP-CIT-003	108607-98-3	1-Bromo-3-[18F]fluoropropane
18F-FP-CIT-005	136794-87-1	Methyl (1R,2S,3S,5S)-3-(4-iodophenyl)-8-azabicyclo[3.2.1]octane-2-carboxylate

OptimisedRoute 4Steps 1 · Total yield 4.082mg(18F-FP-CIT (Free))

Synthetic routes & intermediates Route 4

Code	CAS No.	Intermediate
18F-FP-CIT-009	173378-82-0	Methyl (1R,2S,3S,5S)-3-(4-iodophenyl)-8-[3-[(methylsulfonyl)oxy]propyl]-8-azabicyclo[3.2.1]octane-2-carboxylate
18F-FP-CIT-006	186381-39-5	Methyl (1R,2S,3S,5S)-3-(4-iodophenyl)-8-(3-[[(4-methylphenyl)sulfonyl]oxy]propyl)-8-azabicyclo[3.2.1]octane-2-carboxylate

Frequently asked questions

What are the approved indications of 18F-FP-CIT?

Approved indications include: 帕金森病.

When does the 18F-FP-CIT patent expire?

No public expiry year is available for 18F-FP-CIT yet; this page updates once verified.

How many synthesis routes are recorded for 18F-FP-CIT?

4 synthesis routes are recorded; the shortest is 1 steps with 4.082mg(18F-FP-CIT (Free)) total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy 18F-FP-CIT intermediates?

All intermediates in 18F-FP-CIT routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for 18F-FP-CIT intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-24