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CAS 187668-44-6
4,6-dichloro-5-nitro-2-((3,3,3-trifluoropropyl)thio)pyrimidine
Codes：CANG-018
Application context (from source-drug indications)
冠状动脉血栓坎格雷洛四钠盐心肌梗塞坎格雷洛四钠盐血栓形成坎格雷洛四钠盐急性冠脉综合征坎格雷洛四钠盐冠状动脉病变坎格雷洛四钠盐动脉粥样硬化坎格雷洛四钠盐
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 坎格雷洛四钠盐Cangrelor Tetrasodium | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(2S,3R,4R,5R)-5-(acetoxymethyl)tetrahydrofuran-2,3,4-triyl triacetate→(2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-((2-(methylthio)ethyl)amino)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate→(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((2-(methylthio)ethyl)amino)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)tetrahydrofuran-3,4-diol→N-(2-(methylthio)ethyl)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-6-amine→tributylamine (dichloromethylene)bis(phosphonate)→2-thioxodihydropyrimidine-4,6(1H,5H)-dione→1,1,1-trifluoro-3-iodopropane→2-((3,3,3-trifluoropropyl)thio)pyrimidine-4,6-diol→5-nitro-2-((3,3,3-trifluoropropyl)thio)pyrimidine-4,6-diol→4,6-dichloro-5-nitro-2-((3,3,3-trifluoropropyl)thio)pyrimidine→4,6-dichloro-2-((3,3,3-trifluoropropyl)thio)pyrimidin-5-amine→6-chloro-2-((3,3,3-trifluoropropyl)thio)pyrimidine-4,5-diamine→6-chloro-2-((3,3,3-trifluoropropyl)thio)-9H-purine→2-aminoethanethiol hydrochloride
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications |
|---|---|---|---|---|---|
| Unibest Taizhou GMP-like Site | (2R,3S,4R,5R)-2-(hydroxyMethyl)-5-(6-((2-(Methylthio)ethyl)aMino)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)tetrahydrofuran-3,4-diol Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
| Qualified Partner — East China API Works | Phosphonic acid, P,P'-(dichloromethylene)bis-, compd. with N,N-dibutyl-1-butanamine (1:1) Pharmaceutical Intermediates | 询价 | 询价 | 询价 | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.