坎格雷洛四钠盐
Tier C — Watch / tradeCangrelor Tetrasodium
Targets：P2RY12
Brand：Kengreal、Kengrexal
Indications (approved)：冠状动脉血栓、心肌梗塞、血栓形成、急性冠脉综合征
Regional status
Synthetic routes & intermediates2 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| CANG-007 | 163706-52-3Available | (2R,3R,4R,5R)-2-(6-acetamido-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)-5-(acetoxymethyl)tetrahydrofuran-3,4-diyl diacetate |
| CANG-008 | 542-81-4Available | (2-chloroethyl)(methyl)sulfane |
| CANG-009 | 163706-57-8Available | (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-(N-(2-(methylthio)ethyl)acetamido)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate |
| CANG-010 | 163706-58-9Available | (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((2-(methylthio)ethyl)amino)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)tetrahydrofuran-3,4-diol |
| CANG-011 | 847460-53-1Available | ((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-((2-(methylthio)ethyl)amino)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl dihydrogen phosphate |
| CANG-012 | 81336-70-1Available | tributylamine (dichloromethylene)bis(phosphonate) |
| CANG-013 | - | - |
| CANG-001 | 58-61-7Available | (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol |
| CANG-002 | 146-92-9Available | 6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purine 1-oxide |
| CANG-003 | 57004-06-5Available | (Z)-5-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-N'-hydroxy-1H-imidazole-4-carboximidamide |
| CANG-004 | - | (2R,3R,4S,5R)-2-(6-amino-2-mercapto-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol hydrate |
| CANG-005 | 460-35-5Available | 3-chloro-1,1,1-trifluoropropane |
| CANG-006 | 163706-51-2Available | (2R,3R,4S,5R)-2-(6-amino-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol |
| Code | CAS No. | Intermediate |
|---|---|---|
| CANG-024 | 13035-61-5Available | (2S,3R,4R,5R)-5-(acetoxymethyl)tetrahydrofuran-2,3,4-triyl triacetate |
| CANG-025 | 1830294-26-2Available | (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-((2-(methylthio)ethyl)amino)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate |
| CANG-026 | 163706-58-9Available | (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((2-(methylthio)ethyl)amino)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-9-yl)tetrahydrofuran-3,4-diol |
| CANG-023 | 1830294-25-1Available | N-(2-(methylthio)ethyl)-2-((3,3,3-trifluoropropyl)thio)-9H-purin-6-amine |
| CANG-012 | 81336-70-1Available | tributylamine (dichloromethylene)bis(phosphonate) |
| CANG-014 | 504-17-6Available | 2-thioxodihydropyrimidine-4,6(1H,5H)-dione |
| CANG-015 | 460-37-7Available | 1,1,1-trifluoro-3-iodopropane |
| CANG-016 | - | 2-((3,3,3-trifluoropropyl)thio)pyrimidine-4,6-diol |
| CANG-017 | - | 5-nitro-2-((3,3,3-trifluoropropyl)thio)pyrimidine-4,6-diol |
| CANG-018 | 187668-44-6Available | 4,6-dichloro-5-nitro-2-((3,3,3-trifluoropropyl)thio)pyrimidine |
| CANG-019 | 1830294-22-8Available | 4,6-dichloro-2-((3,3,3-trifluoropropyl)thio)pyrimidin-5-amine |
| CANG-020 | 1830294-23-9Available | 6-chloro-2-((3,3,3-trifluoropropyl)thio)pyrimidine-4,5-diamine |
| CANG-021 | 1830294-24-0Available | 6-chloro-2-((3,3,3-trifluoropropyl)thio)-9H-purine |
| CANG-022 | 156-57-0Available | 2-aminoethanethiol hydrochloride |
Frequently asked questions
What are the approved indications of Cangrelor Tetrasodium?
Approved indications include: 冠状动脉血栓, 心肌梗塞, 血栓形成, 急性冠脉综合征.
When does the Cangrelor Tetrasodium patent expire?
No public expiry year is available for Cangrelor Tetrasodium yet; this page updates once verified.
How many synthesis routes are recorded for Cangrelor Tetrasodium?
2 synthesis routes are recorded; the shortest is 10 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Cangrelor Tetrasodium intermediates?
21 intermediate CAS of Cangrelor Tetrasodium are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Cangrelor Tetrasodium intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-24