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CAS 188416-35-5
3-(6-chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
Codes: VORI-006
Application context (from source-drug indications)
Fungal infectionVoriconazoleCandidaemiaVoriconazoleCandidiasisVoriconazoleAspergillus infectionVoriconazole新型隐球菌感染Voriconazole镰刀菌感染Voriconazole
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Voriconazole | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
ethyl 2-fluoro-3-oxopentanoate→acetic acid;methanimidamide→6-ethyl-5-fluoropyrimidin-4(3H)-one→4-chloro-6-ethyl-5-fluoropyrimidine→1-(2,4-difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethan-1-one→3-(6-chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol→2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
Intermediates available on this site
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