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CAS 198905-09-8
tert-butyl (E)-2-((2R,3S)-3-((tert-butoxycarbonyl)amino)-4-phenyl-2-((4-(pyridin-2-yl)benzoyl)oxy)butylidene)hydrazine-1-carboxylate
Codes：ATAZ-027
Application context (from source-drug indications)
HIV感染硫酸阿扎那韦/考比司他
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 硫酸阿扎那韦/考比司他Atazanavir Sulfate/Cobicistat | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
tert-butyl hydrazinecarboxylate→tert-butyl 2-((2S,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutyl)-2-(4-(pyridin-2-yl)benzyl)hydrazine-1-carboxylate→methyl 4-cyanobenzoate→methyl 4-(pyridin-2-yl)benzoate→4-(pyridin-2-yl)benzoic acid→(isobutyl carbonic) 4-(pyridin-2-yl)benzoic anhydride→(S)-tert-butyl (1-oxo-3-phenylpropan-2-yl)carbamate→(1R,2S)-2-((tert-butoxycarbonyl)amino)-1-cyano-3-phenylpropyl 4-(pyridin-2-yl)benzoate→tert-butyl (E)-2-((2R,3S)-3-((tert-butoxycarbonyl)amino)-4-phenyl-2-((4-(pyridin-2-yl)benzoyl)oxy)butylidene)hydrazine-1-carboxylate→tert-butyl 2-((2S,3S)-3-((tert-butoxycarbonyl)amino)-4-phenyl-2-((4-(pyridin-2-yl)benzoyl)oxy)butyl)hydrazine-1-carboxylate→tert-butyl 2-((2S,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-4-phenylbutyl)-2-(4-(pyridin-2-yl)benzoyl)hydrazine-1-carboxylate
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