CAS 211635-75-5

N-benzyl-2-(4-nitrophenyl)ethan-1-amine

Codes：MIRA-013

Application context (from source-drug indications)

神经性膀胱功能障碍米拉贝隆膀胱过度活动症米拉贝隆

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
米拉贝隆Mirabegron	Tier B — Position early	2029

Position in synthesis routes (up/downstream chain)

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米拉贝隆优化路线steps: 4total yield: 5 g

(R)-2-phenyloxirane→2-(4-nitrophenyl)ethan-1-amine hydrochloride→2-(2-aminothiazol-4-yl)acetic acid→benzaldehyde→N-benzyl-2-(4-nitrophenyl)ethan-1-amine→(R)-2-(benzyl(4-nitrophenethyl)amino)-1-phenylethan-1-ol→(R)-2-((4-aminophenethyl)amino)-1-phenylethan-1-ol

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