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CAS 271-44-3
1,2-Benzodiazole
Codes: Granisetron-025
Application context (from source-drug indications)
Chemotherapy-induced nausea and vomitingGranisetronNauseaGranisetron呕吐Granisetron手术后恶心呕吐GranisetronPostoperative painGranisetronGastroparesisGranisetron
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Granisetron | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-(2-Nitrophenyl)acetic acid→endo-9-Methyl-9-azabicyclo[3.3.1]nonan-3-amine→endo-N-[(1R,3r,5S)-9-Methyl-9-azabicyclo[3.3.1]nonan-3-yl]-2-(2-nitrophenyl)acetamide→endo-2-(2-Aminophenyl)-N-[(1R,3r,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]acetamide→endo-N-[(1R,3r,5S)-9-Methyl-9-azabicyclo[3.3.1]nonan-3-yl]-1H-indazole-3-carboxamide→Iodomethane→1-Methyl-N-[(1R,3R,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]-1H-indazole-3-carboxamide→1,2-Benzodiazole→3-(Trifluoromethyl)-1H-indazole
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