CAS 2755909-85-2

[2-Acetamido-3-(4-bromobenzoyl)-5-sulfophenyl]acetic acid

Codes: Bromfenac Sodium-047

Application context (from source-drug indications)

Inflammatory diseaseBromfenac SodiumPostoperative painBromfenac Sodium眼睛发炎Bromfenac Sodium眼睛疼痛Bromfenac SodiumDry eye syndromeBromfenac Sodium黄斑水肿Bromfenac Sodium

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
Bromfenac Sodium	Tier C — Watch / trade	-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Bromfenac SodiumOptimised routesteps: 5total yield: 27.9g(Bromfenac Sodium (API))

(2-Aminophenyl)acetic acid→(2-Acetamidophenyl)acetic acid→(2-Acetamido-5-sulfophenyl)acetic acid→4-Bromobenzoyl chloride→[2-Acetamido-3-(4-bromobenzoyl)-5-sulfophenyl]acetic acid→[2-Amino-3-(4-bromobenzoyl)phenyl]acetic acid

Intermediates available on this site

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