CAS 313368-85-3

(6bR,10aS)-3-methyl-2,3,6b,7,8,9,10,10a-octahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline

Codes：LUMAT-008

Application context (from source-drug indications)

重度抑郁症甲苯磺酸卢美哌隆抑郁甲苯磺酸卢美哌隆精神分裂症甲苯磺酸卢美哌隆

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
甲苯磺酸卢美哌隆Lumateperone tosylate	Tier C — Watch / trade	2031

Position in synthesis routes (up/downstream chain)

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甲苯磺酸卢美哌隆原研路线steps: 7total yield: /

3,4-dihydroquinoxalin-2(1H)-one→4-nitroso-3,4-dihydroquinoxalin-2(1H)-one→ethyl 4-oxopiperidine-1-carboxylate→ethyl 2-oxo-2,3,9,10-tetrahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline-8(7H)-carboxylate→(6bR,10aS)-ethyl 2-oxo-2,3,6b,7,10,10a-hexahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline-8(9H)-carboxylate→(6bR,10aS)-ethyl 3-methyl-2-oxo-2,3,6b,7,10,10a-hexahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline-8(9H)-carboxylate→(6bR,10aS)-ethyl 3-methyl-2,3,6b,7,10,10a-hexahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline-8(9H)-carboxylate→(6bR,10aS)-3-methyl-2,3,6b,7,8,9,10,10a-octahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline→4-chloro-1-(4-fluorophenyl)butan-1-one

Intermediates available on this site

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Supplier	Product	Price band	MOQ	Lead time	Qualifications
Qualified Partner — East China API Works	(6bR,10aS)-3-Methyl-2,3,6b,7,8,9,10,10a-octahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline Pharmaceutical Intermediates	询价	询价	询价	—

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