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CAS 39021-62-0
1-Methyl-1H-imidazole-5-carbaldehyde
Codes: (VII)115092-6-a
Application context (from source-drug indications)
GlaucomaProxodolol hydrochloride/Pilocarpine Hydrochloride闭角型青光眼Pilocarpine HydrochlorideOcular hypertensionPilocarpine HydrochlorideOpen-angle glaucomaPilocarpine Hydrochloride瞳孔缩小Pilocarpine HydrochlorideSjögren's syndromePilocarpine Hydrochloride虹膜炎Pilocarpine Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Proxodolol hydrochloride/Pilocarpine Hydrochloride | Tier C — Watch / trade | - |
| Pilocarpine Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(2R)-2-Hydroxysuccinic acid→(R)-2-Hydroxysuccinic acid dimethylester→1-Iodoethane→Diethyl (2S,3R)-2-methyl-3-hydroxysuccinate→Dimethyl (2S,3R)-2-ethyl-3-[(4-nitrobenzene-1-sulfonyl)oxy]butanedioate→Dimethyl (3R)-2-bromo-3-ethylbutanedioate→1-Methyl-1H-imidazole-5-carbaldehyde→Methyl (3S,4S)-4-ethyl-2-(1-methyl-1H-imidazol-5-yl)-5-oxooxolane-3-carboxylate→(2S,3R)-2-Ethyl-4-methoxy-3-[(1-methyl-1H-imidazol-5-yl)methyl]-4-oxobutanoic acid
(2R)-2-Hydroxysuccinic acid→(R)-2-Hydroxysuccinic acid dimethylester→1-Iodoethane→Diethyl (2S,3R)-2-methyl-3-hydroxysuccinate→Dimethyl (2S,3R)-2-ethyl-3-[(4-nitrobenzene-1-sulfonyl)oxy]butanedioate→Dimethyl (3R)-2-bromo-3-ethylbutanedioate→1-Methyl-1H-imidazole-5-carbaldehyde→Methyl (3S,4S)-4-ethyl-2-(1-methyl-1H-imidazol-5-yl)-5-oxooxolane-3-carboxylate→(2S,3R)-2-Ethyl-4-methoxy-3-[(1-methyl-1H-imidazol-5-yl)methyl]-4-oxobutanoic acid
Intermediates available on this site
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