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CAS 496816-63-8
N-[(2R)-2-hydroxy-3-(piperidin-1-yl)propoxy]pyridine-3-carbonimidoyl chloride
Codes: (XIII)320339-3-b
Application context (from source-drug indications)
C型尼曼匹克病Arimoclomol Citrate包涵体肌炎Arimoclomol CitrateIII 型戈谢病Arimoclomol CitrateI 型戈谢病Arimoclomol CitrateAmyotrophic lateral sclerosisArimoclomol Citrate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Arimoclomol Citrate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(R)-(-)-Glycidyl m-nitrobenzenesulfonate→Azacyclohexane→N-[(2R)-2-Hydroxy-3-(piperidin-1-yl)propoxy]-1-oxo-1lambda5-pyridine-3-carboximidoyl chloride→N'-hydroxypyridine-3-carboximidamide→N'-[[(2R)-Oxiran-2-yl]methoxy]pyridine-3-carboximidamide→N'-[(2R)-2-Hydroxy-3-(piperidin-1-yl)propoxy]pyridine-3-carboximidamide→N-[(2R)-2-hydroxy-3-(piperidin-1-yl)propoxy]pyridine-3-carbonimidoyl chloride
Intermediates available on this site
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