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CAS 50675-57-5

2,2-Dimethylcyclopropane-1-carbonyl chloride

Codes: Cilastatin Sodium-029

Application context (from source-drug indications)

Infectious diseaseCilastatin Sodium

Source drugs (routes using this intermediate)

DrugTierExpiry
Cilastatin SodiumTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Cilastatin SodiumOptimised routesteps: 6total yield: 1.45g(Cilastatin Sodium-030)
Methyl 3,3-dimethylacrylate→Dibromomethane→Methyl 2,2-dimethylcyclopropane-1-carboxylate→2,2-Dimethylcyclopropane-1-carboxylic acid→2,2-Dimethylcyclopropane-1-carbonyl chloride→(S)-2,2-Dimethylcyclopropanecarboxylic acid→Ethyl 2-diazoacetate→2-Methyl-1-propene→Ethyl (1S)-2,2-dimethylcyclopropane-1-carboxylate→(4R)-4-(1-methylcycloprop-2-en-1-yl)-2-(1-((R)-4-(tert-pentyl)-4,5-dihydrooxazol-2-yl)-1-tritetracontaoxidanylethyl)-4,5-dihydrooxazole

Intermediates available on this site

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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.