CAS 51579-82-9,61618-27-7

2-Amino-3-benzoylbenzeneacetic acid sodium salt monohydrate

Codes: Bromfenac Sodium-017

Application context (from source-drug indications)

Inflammatory diseaseBromfenac SodiumPostoperative painBromfenac Sodium眼睛发炎Bromfenac Sodium眼睛疼痛Bromfenac SodiumDry eye syndromeBromfenac Sodium黄斑水肿Bromfenac Sodium

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
Bromfenac Sodium	Tier C — Watch / trade	-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Bromfenac SodiumProcess routesteps: 7total yield: 493g(Bromfenac Sodium (API))

1H-Indole→3-Bromoindole→1,3-Dihydroindolone→4-Bromobenzonitrile→7-(4-Bromobenzoyl)-1,3-dihydro-2-indolone→[2-Amino-3-(4-bromobenzoyl)phenyl]acetic acid→2-Amino-3-benzoylbenzeneacetic acid sodium salt monohydrate→(2-Amino-3-benzoylphenyl)acetic acid

Intermediates available on this site

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