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CAS 542-78-9
1,3-Propanedial
Codes: (II)115092-10-a
Application context (from source-drug indications)
GlaucomaProxodolol hydrochloride/Pilocarpine Hydrochloride闭角型青光眼Pilocarpine HydrochlorideOcular hypertensionPilocarpine HydrochlorideOpen-angle glaucomaPilocarpine Hydrochloride瞳孔缩小Pilocarpine HydrochlorideSjögren's syndromePilocarpine Hydrochloride虹膜炎Pilocarpine Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Proxodolol hydrochloride/Pilocarpine Hydrochloride | Tier C — Watch / trade | - |
| Pilocarpine Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
Methyl (2S)-2-hydroxybutanoate→1,3-Propanedial→Methyl (2S)-2-ethyl-3-formyl-4-oxobutanoate→Methyl (2S)-2-ethyl-4-hydroxy-3-(hydroxymethyl)butanoate→(3S)-3-Ethyl-4-(hydroxymethyl)oxolan-2-one→5-Chloro-1-methyl-1H-imidazole→(3S)-3-Ethyl-4-(1-methyl-1H-imidazole-5-carbonyl)oxolan-2-one→(3S)-3-Ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]oxolan-2-one
Methyl (2S)-2-hydroxybutanoate→1,3-Propanedial→Methyl (2S)-2-ethyl-3-formyl-4-oxobutanoate→Methyl (2S)-2-ethyl-4-hydroxy-3-(hydroxymethyl)butanoate→(3S)-3-Ethyl-4-(hydroxymethyl)oxolan-2-one→5-Chloro-1-methyl-1H-imidazole→(3S)-3-Ethyl-4-(1-methyl-1H-imidazole-5-carbonyl)oxolan-2-one→(3S)-3-Ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]oxolan-2-one
Intermediates available on this site
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