← Back to patent-cliff list
CAS 577969-77-8
(4aR,6aR,7aR,7bS)-tert-butyl 2,2-dimethyltetrahydro-4H-[1,3]dioxino[5,4-b]oxireno[2,3-d]pyridine-5(4aH)-carboxylate
Codes：MIGA-021
Application context (from source-drug indications)
法布里病米加司他盐酸盐
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 米加司他盐酸盐Migalastat Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
tert-butyl (R)-4-formyl-2,2-dimethyloxazolidine-3-carboxylate→(R)-tert-butyl 4-((R)-1-hydroxyallyl)-2,2-dimethyloxazolidine-3-carboxylate→tert-butyl ((4R,5R)-2,2-dimethyl-4-vinyl-1,3-dioxan-5-yl)carbamate→3-iodoprop-1-ene→tert-butyl allyl((4R,5R)-2,2-dimethyl-4-vinyl-1,3-dioxan-5-yl)carbamate→(4aR,8aR)-tert-butyl 2,2-dimethyl-6,8a-dihydro-4H-[1,3]dioxino[5,4-b]pyridine-5(4aH)-carboxylate→(5R,6R)-tert-butyl 5-hydroxy-6-(hydroxymethyl)-5,6-dihydropyridine-1(2H)-carboxylate→(4aR,6aR,7aR,7bS)-tert-butyl 2,2-dimethyltetrahydro-4H-[1,3]dioxino[5,4-b]oxireno[2,3-d]pyridine-5(4aH)-carboxylate
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.