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CAS 59091-92-8

N-[4-(2-Acetamido-4-oxo-1,4-dihydropteridin-6-ylmethyleneamino)benzoyl]-L-glutamic acid dimethyl diester

Codes:Folic Acid-021

Application context (from source-drug indications)

原发性高血压马来酸依那普利/叶酸巨幼红细胞性贫血叶酸叶酸缺乏叶酸神经管缺损叶酸贫血叶酸热潮红叶酸高同型半胱氨酸血症叶酸

Source drugs (routes using this intermediate)

DrugTierExpiry
Enalapril Maleate/Folic AcidEnalapril Maleate/Folic AcidTier C — Watch / trade-
Folic AcidFolic AcidTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Enalapril Maleate/Folic Acid优化路线steps: 4total yield: /
2-Amino-4-oxo-3,4-dihydropteridine-6-carbaldehyde→N-(6-Formyl-4-oxo-1,4-dihydropteridin-2-yl)acetamide dihydrate→N-(4-Aminobenzoyl)-L-glutamic acid dimethyl diester→N-[4-(2-Acetamido-4-oxo-1,4-dihydropteridin-6-ylmethyleneamino)benzoyl]-L-glutamic acid dimethyl diester→N-[4-(2-Acetamido-4-oxo-1,4-dihydropteridin-6-ylmethylamino)benzoyl]-L-glutamic acid dimethyl diester
Folic Acid优化路线steps: 4total yield: /
2-Amino-4-oxo-3,4-dihydropteridine-6-carbaldehyde→N-(6-Formyl-4-oxo-1,4-dihydropteridin-2-yl)acetamide dihydrate→N-(4-Aminobenzoyl)-L-glutamic acid dimethyl diester→N-[4-(2-Acetamido-4-oxo-1,4-dihydropteridin-6-ylmethyleneamino)benzoyl]-L-glutamic acid dimethyl diester→N-[4-(2-Acetamido-4-oxo-1,4-dihydropteridin-6-ylmethylamino)benzoyl]-L-glutamic acid dimethyl diester

Intermediates available on this site

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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.