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CAS 5985-28-4
4-[1-Hydroxy-2-(methylamino)ethyl]phenol hydrogen chloride
Codes: (VIII)275500-2-a
Application context (from source-drug indications)
Allergic reactionEpinephrine intranasal spray (ARS Pharmaceuticals)Chronic urticariaEpinephrine intranasal spray (ARS Pharmaceuticals)UrticariaEpinephrine intranasal spray (ARS Pharmaceuticals)AsthmaEpinephrine intranasal spray (ARS Pharmaceuticals)Respiratory tract infectionEpinephrine intranasal spray (ARS Pharmaceuticals)
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Epinephrine intranasal spray (ARS Pharmaceuticals) | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1,2-Dihydroxybenzene→2-Chloranylethanoyl chloride→2-Chloro-1-(3,4-dihydroxyphenyl)ethanone→N-Benzyl-N-methylamine→2-[Benzyl(methyl)amino]-1-(3,4-dihydroxyphenyl)ethan-1-one→(±)-2-(3,4-Dihydroxyphenyl)-2-hydroxy-N-methylethylamine→(+)-4-[1(S)-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol→4-[1-Hydroxy-2-(methylamino)ethyl]phenol hydrogen chloride→N-Boc-synephrine→N-Boc-racepinephrine
Intermediates available on this site
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